We invite proposals in basic, clinical, behavioral, substance use, and implementation science research that align with the priorities of the Office of AIDS Research (OAR) and Ending the HIV Epidemic. Clinical trials are not allowed. Faculty with primary appointments at WashU, SLU, and HSSU, and who are early-stage investigators or who are established investigators new to HIV/AIDS research are eligible to apply. Eligible investigators who are members of racial or ethnic groups historically under-represented in research and/or sexual and gender minority groups are particularly encouraged to apply.